I am deeply ingrained in these types of topics, as a social scientist, philosopher, researcher, sociologist and more. I have written articles such as these as well, as a critical realist. Have you looked into the works of Tesla? A genius far ahead of his time, recognized that there is such a thing as Universal knowledge. This is the guy who invented the alternating electrical current system (and more).
Science, nor any discipline, should never be so closed off from the perspective that, in truthful fashion, as quantum physics begins to explore, we are simply instruments for advancement, but our knowledge will always be limited by our perspective, and our views on the world.
And yes, the only certainty of life, is that we are not certain at all.